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Abstract #2167

Loss of lateral asymmetry in the brain of mouse models of autism

Jacob Ellegood1, Benjamin C Darwin1, Matthijs C Van Eede1, Mark Henkelman1,2, and Jason P Lerch1,2

1Hospital for Sick Children, Toronto, ON, Canada, 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Examination of lateral asymmetry differences in mouse models related to Autism. Using 42 different mouselines as a representative sample of an autistic population, we show a loss of asymmetry in the mutant mice compared to wild-type that may be indicative of functional and/or behavioural variations.

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