Abstract #2202

Default Mode Sub-network in Brain Tumor: A Resting State fMRI Study

Xiao Ling¹, Chen Niu¹, Pan Lin², Kun Zhang³, Xin Liu⁴, Wenfei Li¹, Liping Guo¹, and Ming Zhang*¹

¹Department of Medical Imaging, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China, ²Key Laboratory of Biomedical Information Engineering of Education Ministry, Institute of Biomedical Engineering, Xi’an Jiaotong University, Xi'an, People's Republic of China, ³Department of Electronics Engineering, Northwestern Polytechnical University, Xi'an, People's Republic of China, ⁴Technical University Munich

The aim of the study was to observe the activation of DMN in patients with different types and location brain tumors, and as so to investigate whether the type and location of tumor would affect DMN spatial distribution. In our study, we compared the spatial distribution of DMN both glioma and meningioma. Finally, our findings show that DMN integrity is impaired as a result of tumor, and the DMN spatial distribution could be affected by the location of the brain tumor.

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