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Abstract #2217

Exploring the distribution of inflow and outflow bloodstream type in pituitary adenoma by dynamic contrast-enhanced MRI

Miaomiao Wang1, Rihua Jiao2, Yanan Li1, Congcong Liu1, Jianxin Guo1, Chao Jin1, and Jian Yang1

1Department of Diagnostic Radiology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People's Republic of China, 2ISN Lab, Xidian University

In this study, a new approach for assessing distribution of bloodstream inflow and outflow type based on the three-time point (3TP) method was used to semi-quantitative analysis of the microcirculation characteristics in whole pituitary adenoma by dynamic contrast-enhanced MRI (DCE-MRI). The volume percentage of persistently enhancing type of time-intensity curve (TIC) in adenoma was higher than normal region. Meanwhile, adenomas with hyperprolactinemia were shown a significant decrease of volume percentage in speed up the downhill type when compared with the adenoma without hyperprolactinemia. This method could identify the different distribution of vascularity between normal pituitary and subtype of adenoma.

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