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Abstract #2220

Radiographic Atlas of Tumor Growth Pattern in Glioblastoma

Morteza Esmaeili1, Anne Line Stensjøen1, Erik Magnus Berntsen1, Ole Solheim1,2,3, and Ingerid Reinertsen3,4

1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, NTNU, Trondheim, Norway, 2Department of Neurosurgery, St. Olav’s University Hospital, Trondheim, Norway, 3Norwegian National Advisory unit for Ultrasound and Image Guided Therapy, St. Olav’s University Hospital, Trondheim, Norway, 4Department of Medical Technology, SINTEF, Trondheim, Norway

In this study we assess the growth pattern of one of the most aggressive brain tumor in adults. Surgery is a standard of care for these patients, and understanding the prominent growth direction of tumor lesions can eventually benefit surgical planning. Contrast-enhanced MR data at two time-points of diagnosis and pre-operation were analyzed to derive mean 3D vector field demonstrating the growth directions. A DTI white matter (WM) atlas was used to investigate the degree of agreement and alignment of the generated vector field towards white matter fibers.

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