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Abstract #2223

Imaging Characteristics According to the IDH Mutation and 1p19q Codeletion Status of Lower Grade Gliomas

Yae Won Park1, Sung Soo Ahn1, and Seung-Koo Lee1

1Yonsei University College of Medicine, Seoul, Korea, Republic of

Preoperative prediction of genotypic classification with MRI is useful because IDH mutation and 1p/19q codeletion status are important prognostic and predictive factors in lower-grade gliomas (WHO grade II and III). In this study we found that various preoperative imaging features including lobar/nonlobar or central location, enhancement characteristics, tumor margin, diffusion characteristics, ependymal/cortical involvement were different between IDH-wildtype and IDH-mutant group. Therefore preoperative MRI may be helpful to predict IDH mutation status in lower-grade gliomas.

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