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Abstract #2222

The diagnostic performance of DCE-MRI in differentiating high-from low-grade gliomas: A systematic review and meta-analysis

Zhe Liu1, Xiang Li1, Ting Liang1, Tong Yi Bian1, Miao Miao Wang1, Li Qin Sun1, Gang Niu1, and Jian Yang1

1Department of Diagnostic Radiology, the first affiliated hospital of XI'AN jiaotong universityDepartment of Diagnostic Radiology, XI'AN, People's Republic of China

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been provided for noninvasive assessment of different grade of gliomas. But the diagnostic performance of this new approach was variant among the recent reports. This study included 10 DCE-MRI studies regarding to differentiating high grade gliomas (HGGs) from low grade gliomas (LGGs). The meta-analysis results demonstrated that parameters of DCE-MRI have high diagnostic performanc (Ktrans and Ve) in distinguishing HGGs from LGGs. DCE-MRI can be used as an important tool for the assessment of neovascular permeability and for the pre-operative grading of glioma.

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