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Abstract #2232

Cerebral blood flow measurements in patients with depression and comorbid hypertension in depression using 3D arterial spin labeling

Ying Liu1, Huishu Yuan1, Xiangzhu Zeng1, Zheng Wang1, and Lizhi Xie2

1Radiology, Peking University Third Hospital, Beijing, People's Republic of China, 2GE Healthcare, MR Research China, Beijing, People's Republic of China

The aim of this study is to explore the potential differences of the quantitative CBF values among patients with depression, patients with hypertension and patients with comorbid hypertension in depression by using whole brain 3D PCASL and to investigate the correlation between CBF values and degrees of depression. The results indicate that CBF values decrease in frontal and parietal lobes in patients with comorbid hypertension in depression, whereas not in patients with depression or patients with hypertension, hypertension may play a synergistic action in the progress of depression.

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