The aim of this study is to explore the potential differences of the quantitative CBF values among patients with depression, patients with hypertension and patients with comorbid hypertension in depression by using whole brain 3D PCASL and to investigate the correlation between CBF values and degrees of depression. The results indicate that CBF values decrease in frontal and parietal lobes in patients with comorbid hypertension in depression, whereas not in patients with depression or patients with hypertension, hypertension may play a synergistic action in the progress of depression.
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