Possible effects on the structures of visual cortex using high-resolution anatomical MRI have not been established so far. The aim of this study was to investigate volumetric alterations in visual cortex of RP patients using voxel based morphometry (VBM). Our results demonstrated that RP is associated with degeneration of structures in the visual cortex, and prevention of visual cortical degeneration may need to become a new therapeutic goal for RP patients, which may have significant meaning for clinical to guide RP patients' treatment in a more reasonable way in future.
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