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Abstract #2282

Correlation of fetal MRI with neurodevelopmental outcome in fetuses with ventriculomegaly

Xin Mu1, Hosung Kim1, Duan Xu1, and Orit Glenn1

1Department of Radiology and Biomedical Imaging, University of California San Francisco, SAN FRANCISCO, CA, United States

Ventriculomegaly (VM) is the most common referred abnormality for fetal MRI and may be isolated or associated with additional abnormalities. We performed MR exams in 46 fetus diagnosed with isolated VM on ultrasound (US) and assessed neurodevelopmental outcome at 12 and 30 months with Bayley-III. Ventricle size (VS) measured by US and MRI and Bayley-III scores were analyzed using linear models. VS measured at older gestational age and longitudinal VS changes on MRI predicted outcome better than at younger age and on US. The presence of additional brain findings on fetal MRI significantly correlated with outcome and improved outcome predictability.

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