Abstract #2288

Assessing white matter tract development in formula fed versus breastfed infants at 1 month and 3 months

Giang-Chau Ngo^1,2, Clarisa Carruthers³, Catherine Vu³, Alex Cerjanic^1,2, Monica Muthaiya¹, Marie Drottar³, Jonathan Litt⁴, Ivan Frantz⁴, Ryan Larsen², Borjan Gagoski³, P. Ellen Grant³, and Bradley P. Sutton^1,2

¹Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Boston Children’s Hospital, Boston, MA, United States, ⁴Beth Israel Deaconness, Boston, MA, United States

Diffusion Tensor Imaging and Tract-Based Spatial Statistic on FA, RD and AD were applied to investigate white matter development in formula fed infants and breast fed infants. Thirty-six infants (thirty breast fed and six formula fed) were scanned at 1 month and twenty-two (twelve breast fed and ten formula fed) at 3 months. Increased FA and decreased RD values were observed in breast fed infants at 1 month with differences becoming insignificant at 3 months.

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