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Abstract #2328

Evaluation of PROspective MOtion correction on high-resolution 3D-FLAIR acquisitions in epilepsy patients

Sjoerd B Vos1,2, Caroline Micallef3, Frederik Barkhof1,3,4, Andrea Hill2,5, John S Duncan2,5, and Sebastien Ourselin1,6

1Translational Imaging Group, CMIC, University College London, London, United Kingdom, 2Epilepsy Society MRI Unit, Chalfont St Peter, United Kingdom, 3Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom, 4Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, Netherlands, 5Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, United Kingdom, 6Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom

FLAIR is the single most sensitive MRI contrast to detect lesions underlying focal epilepsies but 3D sequences used to obtain isotropic high-resolution images are susceptible to motion. PROspective MOtion correction (PROMO) was applied to 3D-FLAIR scans in epilepsy patients to evaluate clinical benefit. Two radiologists reviewed 40 scans without and 80 with PROMO assessing six criteria on a seven-point Likert scale. PROMO scans can achieve near-identical image quality as nonPROMO scans, but intensity inhomogeneity was generally poor using PROMO. The percentage of scans with bad image quality was 4-fold lower with PROMO than without on the other five criteria.

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