It is reported that the brain always be an injured target organ in end-stage renal disease (ESRD) patients, a series of pathophysiologic changes easily make the iron accumulate in brain and accelerate the brain degeneration, which results in the brain cognitive function decline. T1rho relaxation time can reflect the changes of the macromolecular substance content and can be shorten by the Paramagnetic component, which makes it the ability to distinguish the healthy controls from ESRD patients. Voxel based measurement as a classical methods to verify the volume of each brain section, which can be also used to represent the structure of the brain. Combined with the results of neuropsylogical tests, T1rho mapping can better characterize the hippocampus in ESRD patients and the conclusions give a support for considering that the brain function changes earlier than structure changes.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords