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Abstract #2401

Comparison of inhomogeneous magnetization transfer imaging with myelin water imaging (MWI) and diffusion tensor imaging (DTI)

Ece Ercan1, Gopal Varma2, Burkhard Maedler3, Ivan E Dimitrov4,5, Marco Pinho1,4, Ben Wagner1, Elizabeth Davenport1, Joseph Maldjian1, Robert E Lenkinski1,4, and Elena Vinogradov1,4

1Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Radiology, Division of MR Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 3Philips Healthcare, Germany, 4Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 5Philips Healthcare, Gainesville, FL, United States

Inhomogeneous magnetization transfer (ihMT) imaging is an enhanced magnetization transfer technique, which has been shown to produce a higher white/gray matter contrast compared to conventional MT methods. This contrast is thought to be originating from dipolar order effects in myelinated tissues. In this study we compare ihMT with myelin water imaging and diffusion tensor imaging.

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