We explored the utility and complementarity of different diffusion and relaxometry metrics for cortical imaging. The following metrics were assessed for correlation: mean kurtosis (MK) from diffusion kurtosis imaging, intra-cellular volume fraction (ICVF), from the NODDI model, intra-neurite volume fraction (VINT), from the multi-compartment microscopic diffusion imaging (MCMICRO) model, R1 (=1/T1), R2* (=1/T2*) and the ratio of T1w/T2w images. Some global similarities can be seen between most cortical maps, while some features that suggest complementarity between diffusion and relaxometry maps were also observed. This study emphasizes the importance of better understanding and characterising the relationship between different MRI-derived metrics.
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