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Abstract #2414

Head-to-head comparison of ferumoxytol and gadolinium-enhanced intracranial MRA at 7T vs. non-contrast TOF

Daniel Schwartz1, Ramon F Barajas2, John Grinstead3, Laszlo Szidonya4, Jenny Firkins4, William Rooney5, and Edward Neuwelt6

1Neurology/AIRC, OHSU, Portland, OR, United States, 2Radiology/AIRC, OHSU, 3Siemens Medical, 4Neurology, OHSU, 5AIRC, OHSU, 6Neurology/Neurosurgery, OHSU

7T imaging of neurovasculature with TOF affords sub-millimeter resolution and can make it possible to visualize extremely small vessels such as the lenticulostriate arteries; however, TOF can be hampered by flow and pulsation artifacts. K-space reordering and the administration of a contrast agent can greatly reduce these artifacts while still allowing for small vessel conspicuity. We acquired gadolinium and ferumoxytol-based MRA alongside TOF in three patients and two radiologists rated vessel conspicuity and artifact. Artifacts were diminished with contrast, though there were no differences in artifact due to k-space reordering, and vessel conspicuity was high in all acquisitions.

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