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Abstract #2432

Increased Anisotropy as Possible Compensatory Plasticity of Ventral Thalamic Nuclei to Gait Disturbance in Patients with Idiopathic Normal Pressure Hydrocephalus

Ping-Huei Tsai1,2,3, Yung-Chieh Chen4, Shih-Wei Chiang5,6, Hua-Shan Liu3,7, Ming-Chung Chou8, Fei-Ting Hsu2,3, Yu-Chieh Kao1,3, Chia-Feng Lu1,3, Hsiao-Wen Chung6, and Cheng-Yu Chen1,2

1Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 2Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 3Translational Imaging Research Center, College of Medicine, Taipei Medical University, Taipei, Taiwan, 41Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 5Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, 6Graduate Institute of Biomedical Electrics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 7School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan, 8Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

This study allows improved localization of sensorimotor-related thalamic nuclei providing non-invasive evaluation of the microstructural changes of thalamus after iNPH, which may have a potential to contribute to early diagnosis and better prognosis prediction in the patients.

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