Abstract #2466

PC-MRI OF CEREBRAL BLOOD AND CSF FLOW VERSUS INTRACRANIAL PRESSURE MONITORING IN HYDROCEPHALUS PATIENTS

Armelle Lokossou¹, Olivier Baledent¹, Simon Garnotel¹, Gwenaël Pagé¹, Laurent Balardy², Zofia Czosnyka³, Pierre Payoux⁴, and Eric A. Schmidt^5,6

¹Departments of Medical Image Processing, BioFlowImage Laboratory, University Hospital of Picardie Jules Verne, AMIENS, France, ²Department of Internal Medicine and Gerontology, Toulouse University Hospital, Toulouse, France, ³Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., ⁴Department of Nuclear Medicine, CHU Toulouse, Purpan University Hospital, Toulouse, France, ⁵UMR 1214 – INSERM/UPS – TONIC Toulouse Neuro-Imaging Center, Toulouse, France, ⁶Departments of Neurosurgery, University Hospital of Toulouse, France

The neurosurgical guidelines recommend low invasive intracranial pressure (ICP) monitoring with infusion tests to detect CSF dynamics alteration. In this study, we investigate how PC-MRI could be helpful in intracranial flow investigations. Eighty-three patients suspected of active hydrocephalus underwent the conventional ICP investigations. All the patients had also the day before, a rapid and simple PC-MRI to assess their cerebral blood and CSF flows. We found that patients who presented altered CSF dynamics (observed by ICP monitoring) presented also the smallest cervical CSF oscillations in the population. PC-MRI brings easy, quick and non-invasive complementary information to investigate the craniospinal dynamic.

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