Earlier studies using fMRI have shown the existence of a modular structure for different brain networks. However, no information exist about hierarchical modular structure of functional connectivity networks in patients with Parkinson’s disease(PD). Using percolation analysis, we found a shift in the hierarchical modular structure of functional connectivity networks in patients with PD. A shift in the modules in caudal-rostral direction in the PD group of motorically affected patients, alongside rearrangement of connector hubs and provincial hubs in PD patients was observed. Potential application of network properties observed here, as predictors of subsequent disease progression is currently being investigated.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords