Abstract #2515

Mathematical Modeling for Evaluating Gustatory Stimulation of Parotid Gland by Proton Density MRI

Yu-Chia Cheng¹, Yi-Jui Liu², Yi-Hsiung Lee^3,4, Hing-Chiu Chang⁵, Hui-Chu Chiu⁶, Ta-Wei Chiu⁷, Kang Hsu⁸, Hsian-He Hsu^4,9, and Chun-Jung Juan^4,9

¹Master 's Program of Biomedical Informatics and Biomedical Engineering of Feng Chia University, Taichung, Taiwan, Taichung, Taiwan, ²Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China, ³Ph.D. program in Electrical and Communication Engineering in Feng Chia University, Taichung, Taiwan, Republic of China, ⁴Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China, ⁵Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, ⁶Ph.D. program of Technology Management, Chung Hua University, Hsinchu, Taiwan, Republic of China, ⁷Department of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China, ⁸Department of Dentistry, National Defense Medical Center, Taipei, Taiwan, Republic of China, ⁹Department of Radiology, National Defense Medical Center, Taipei, Taiwan, Republic of China

The parotid gland function is evaluated by gustatory stimulation using scintigraphy in clinic. Due to the saliva secretion of parotid, it is supposed to measure the water component of parotid gland using PD MRI instead of scintigraphy. Normally the drop magnitude and recover rate of signal-time curve after gustatory stimulation was used to evaluate the function of parotid gland. For more physiology and quantitative parameters of characteristics of signal-time curve, we developed a mathematical model for drainage and refill of a toilet tank to quantify the parotid gland function in this study.

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