Residual tumour detection in post-treatment granulation tissue by using multiple diffusion models in head and neck squamous cell carcinoma patients

We assessed the utility of diffusion parameters obtained by multiple fitting models for the determination of the presence of the residual tumor after the curative chemoradiation in patients with head and neck squamous cell carcinoma (HNSCC). The result of the current study revealed the center of the Gaussian distribution of diffusion coefficient (D_s) in the statistical diffusion model and diffusion heterogeneity parameter in the stretched exponential model were respectively indicated as an independent predictor for the determination of the presence of residual tumor. This result will be useful information for the daily clinical follow-up in patients with HNSCC.