Abstract #2528

Inhomogeneous Magnetization Transfer (ihMT) in normal-appearing tissue correlates with clinical EDSS score of MS patients.

Elise Van Obberghen¹, Samira Mchinda¹, Arnaud le Troter¹, Valentin H. Prevost¹, Patrick Viout¹, Elisabeth Soulier¹, Maxime Guye¹, Gopal Varma², David C. Alsop², Jean-Philippe Ranjeva¹, Jean Pelletier³, Olivier M. Girard¹, and Guillaume Duhamel¹

¹Aix-Marseille Univ, CNRS, CRMBM UMR 7339, Marseille, France, ²Radiology, Division of MR Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ³Aix Marseille Univ, APHM, Hôpital La Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, Marseille, France

The present study was aimed at evaluating the potential of ihMT (inhomogeneous Magnetization transfer) contrast in characterizing the severity of MS disease, and investigating possible correlations between ihMT and the clinical disability score.

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