The reduction of noise is of high value for FLAIR² images because the multiplication of FLAIR and T2 images will always result in an image with a reduced Signal-to-noise-ratio. Here different filter methods, like Gaussian, Wiener and Total Generalized Variation were used to demonstrate noise reduction. The drawback of noise reduction is a blurring effect of anatomical structures. In this study we demonstrate that TGV filtering has certain advantages compared to Wiener and Gaussian techniques in research and clinical applications.
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