Abstract #2549

Rapid, high-resolution imaging of the central veins in multiple sclerosis at 1.5T, 3T, and 7T

Pascal Sati¹, Sunil Patil², Souheil I Inati³, Govind Nair¹, Gunnar Krueger⁴, and Daniel S Reich¹

¹Translational Neuroradiology Section, NINDS, National Institutes of Health, Bethesda, MD, United States, ²Siemens Medical Solutions, HC NAM USA DI MR COLLAB, Bethesda, MD, United States, ³InatiAnalytics, Potomac, MD, United States, ⁴Siemens Medical Solutions, HC NAM USA DI MR COLLAB NE, Boston, MA, United States

The central vein sign (CVS) detected by magnetic resonance imaging (MRI) may aid with the diagnosis of multiple sclerosis (MS). The ability to detect central veins in the brain at any magnetic field strengths would open the pathway for future large-scale research studies, and potentially routine clinical use, of the CVS for MS diagnosis. In this study, a fast high-isotropic-resolution, whole-brain T₂^*-weighted segmented echo-planar-imaging acquisition was implemented at 1.5T, 3T and 7T. Central veins inside multiple sclerosis lesions were detected at all three different field strengths.

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