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Abstract #2559

High-resolution spinal DTI imaging using RESOLVE sequence in multiple sclerosis and clinical isolated syndrome

Ningnannan Zhang1, Zhang Zhang1, Tianyi Qian2, Wen Qin1, Qiuhui Wang1, and Chunshui Yu1

1Department of Radiology, Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin, People's Republic of China, 2MR Collaborations NE Asia, Siemens Healthcare, Beijing, People's Republic of China

This study reports the preliminary application of high-resolution diffusion tensor imaging (DTI) using readout segmentation of long variable echo trains (RESOLVE) sequence for spinal cord imaging in patients with demyelinating conditions. Patients with clinical isolated syndrome (CIS) and multiple sclerosis (MS) were recruited in order to investigate image evidences in early stages and the progression of the disease. The results of DTI analyses demonstrate that MS is characterized by diffuse axonal compensation in the spinal cord.

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