Soman is a chemical warfare nerve agent that is categorized as a weapon of mass destruction. Nerve agents are potent irreversible inhibitors of acetylcholinesterase and exposure can be extremely lethal. At a sub-lethal dose, our understanding of the neurological effect is limited. To understand the soman associated physiological changes, MRI was used to quantify the cerebral blood flow after a convulsive dose of soman.
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