Abstract #2572

Direct Localization Human Pedunculopontine Nucleus Using 7T, Coordinate and Fiber Tracking Validation

Fei Cong^1,2, Jiawei Wang³, Zhangyan Yang^1,2, Yan Zhuo¹, Bo Wang¹, Yuqing Zhang³, and Lin Chen¹

¹State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China, ²Graduate University, Chinese Academy of Sciences, Beijing, People's Republic of China, ³Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China

The pedunculopontine nucleus (PPN), as a potential Deep brain stimulation (DBS) target for the patients to improve gait and posture. Until now, only a few results of the location of PPN has been published. In this study, 7T ultra-high field MR system and high resolution MP2RAGE sequence were used to locate the PPN by a direct view, manually measurement and fiber tracking method were used to verify the results. The results showed a clear and accurate location of PPN.

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