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Abstract #2572

Direct Localization Human Pedunculopontine Nucleus Using 7T, Coordinate and Fiber Tracking Validation

Fei Cong1,2, Jiawei Wang3, Zhangyan Yang1,2, Yan Zhuo1, Bo Wang1, Yuqing Zhang3, and Lin Chen1

1State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China, 2Graduate University, Chinese Academy of Sciences, Beijing, People's Republic of China, 3Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China

The pedunculopontine nucleus (PPN), as a potential Deep brain stimulation (DBS) target for the patients to improve gait and posture. Until now, only a few results of the location of PPN has been published. In this study, 7T ultra-high field MR system and high resolution MP2RAGE sequence were used to locate the PPN by a direct view, manually measurement and fiber tracking method were used to verify the results. The results showed a clear and accurate location of PPN.

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