MR thermometry, based on proton resonance frequency (PRF) shift, can be achieved by the phase subtraction between pretreatment baseline images and treatment images. However, breathing motion leads to phase errors that may corrupt temperature measurements. We propose the use of a hybrid MR-ultrasound imaging setup and reconstruction algorithm to provide the phase reference required for PRF thermometry in moving organs. The generated synthetic MR-ultrasound images match the acquired images in all respect except for the fact that they do not contain any heating information, and thus provide a valuable non-heated phase reference from which temperature changes can be quantified.
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