Abstract #2600

Detection of temperature induced viscoelasticity changes using MR acoustic radiation force impulse imaging

Lorne Wyatt Hofstetter¹, Henrik Odeen², Joshua de Bever³, Hailey McLean², Allison Payne¹, and Dennis L Parker¹

¹Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ²Department of Radiology and Imaging Sciences, University of Utah, ³Department of Radiology, Stanford University

MR acoustic radiation force impulse (MR-ARFI) imaging, which measures tissue displacement caused by the concentrated force of a focused ultrasound (FUS) beam, has been used to locate and characterize the ultrasound focus. It has also been used to measure and assess changes in tissue elastic properties. We hypothesize that localized heating may denature elastic properties of tissues, and convert the elastic displacement caused by FUS to a form of viscous streaming. In this work, we propose using 3D GRE MR-ARFI with a unique timing scheme, to quickly and efficiently detect temperature induced viscoelasticity changes in a gelatin phantom during FUS heating.

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