Abstract #2741

Simple quantification using the myocardium-to-lumen signal ratio in diffuse myocardial fibrosis of non-ischemic cardiomyopathies: Correlation with T1 mapping derived ECV

Yoshiaki Morita¹, Naoaki Yamada¹, Teruo Noguchi², Yoshiaki Watanabe¹, Tatsuya Nishii¹, Atsushi Kono¹, and Tetsuya Fukuda¹

¹Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, ²Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

Myocardial T1 mapping has recently been applied to the quantification of extracellular volume fraction (ECV) and has shown potential for the detection of myocardial fibrosis. However, for the measurement of ECV, additional scans of pre- and post-contrast T1 mapping are necessary, and the post-processing procedure is time consuming. In this study, the myocardium-to-lumen signal ratio (M/L) in conventional late gadolinium enhancement images with fixed inversion time showed acceptable levels of correlation with ECV obtained by the T1 mapping in non-ischemic cardiomyopathy, suggesting that M/L has the potential to allow for simple quantification of the fibrotic change in non-ischemic cardiomyopathies.

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