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Abstract #2740

Assessment of myocardial inflammation in cardiac sarcoidosis using early gadolinium enhancement

Yoshiaki Morita1, Naoaki Yamada1, Teruo Noguchi2, Yoshiaki Watanabe1, Tatsuya Nishii1, Atsushi Kono1, and Tetsuya Fukuda1

1Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan, 2Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan

In patients with cardiac sarcoidosis, assessment of the activity of myocardial inflammation is as crucial as the choice of therapeutic strategy and monitoring of therapeutic effects. It is known that early gadolinium enhancement (at 2–5 minutes after gadolinium administration) can visualize myocardial inflammation and/or edema such as in acute myocarditis and acute myocardial infarction. In this study, images of gadolinium enhancement at 2 minutes delay were significantly associated with findings regarding active inflammation, suggesting that early gadolinium enhancement has the potential to act as a marker of inflammation activity in cardiac sarcoidosis.

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