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Abstract #2772

MR Imaging of Vasa Vasorum During Lipid-Lowering Therapy to Carotid Unstable Plaque: A Prospective Study in Chinese Patients

Cui Bao1, Cui Jinguo1, and Cai Jianming2

1Bethune international peace hospital, Shi jiazhuang, People's Republic of China, 2Chinese PLA general hospital

Carotid plaque vasa vasorum angiogenesis from adventitia may be influenced by inflammation, could promote intraplaque hemorrhage and decrease the thickness of fibrous cap, finally, the cap is prone to rupture. Drug therapy and assessment to the vulnerable plaque, in vivo, would be of major clinical interest. To investigate whether lipid therapy leads to changes in vasa vasorum characteristics of carotid unstable plaque in chinese patients, as measured by using dynamic contrast-enhanced (DCE) MRI. Focus on inflammation to monitor the early beneficial therapy using vasa vasorum MR imaging, biomarker in vivo.

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