Abstract #2791

Quantitative 3D Dynamic Contrast Enhanced (DCE) Imaging of Carotid Vessel Wall by Fast T1 Mapping

Nan Wang^1,2, Anthony Christodoulou¹, Yibin Xie¹, and Debiao Li^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

Dynamic contrast enhanced (DCE) MRI is a promising technique to quantitatively evaluate the inflammatory status of atherosclerosis noninvasively. However, its demanding sampling requirement leads to sacrifices in slide resolution, coverage, and/or temporal resolution in the applications to vessel wall imaging. In this work we designed accelerated dynamic T1-mapping technique using Low Rank Tensor (LRT) framework to achieve 3D high-resolution quantitative DCE of the carotid arteries.

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