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Abstract #2831

Distribution of 4D flow MRI-derived wall shear stress and oscillatory shear index and its relation with the ascending aorta dilation in bicuspid valve patients.

Lydia Dux-Santoy 1, Andrea Guala2, José F. Rodríguez-Palomares 2, Julio Sotelo 3, Daniel E. Hurtado 4, Sergio Uribe 5, and Arturo Evangelista 2

1Hospital Universitari Vall d´Hebron, Department of Cardiology. Vall d’Hebron Institut de Recerca (VHIR). Universitat Autònoma de Barcelona. Barcelona. Spain, barcelona, Spain, 2Hospital Universitari Vall d´Hebron, Department of Cardiology. Vall d’Hebron Institut de Recerca (VHIR). Universitat Autònoma de Barcelona. Barcelona. Spain, 3Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Department of Electrical Engineering, Pontificia Universidad Católica de Chile, 4Department of Structural and Geotechnical Engineering, Pontificia Universidad Católica de Chile, 5Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Department of Electrical Engineering, Pontificia Universidad Católica de Chile.

Elevated WSS is atheroprotective but implies greater medial degradation. Lower WSS degenerates endothelium and determines aneurysm area with lower dilation and rupture risk. OSI distinguishes aneurysm for rupture. Through 4D-flow MRI we analyze WSS and OSI ascending aortic regional differences in 27 BAV patients and 11 controls. Despite average WSS and OSI do not different among TAV and BAV, RL-BAV and RN-BAV and dilated and non-dilated BAV, regional differences have been found. Of most interest, dilated BAVs have partially overlapping regions of lower WSS and high OSI in the distal-anterior ascending aorta which may explain ascending aorta dilation morphotype

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