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Abstract #2850

The Magnitude of Static Phantom Corrections for Velocity Encoded Phase Contrast Cine MRI and Clinical Importance

Evan A Nelson1, Li-Yueh Hsu1, Anna Noreuil1, Sara E Berger2,3, Marcus Y Chen1, W. Patricia Bandettini1, Sujata M Shanbhag1, Shahryar G Saba4, Giancarlo Serafini1, Christine Mancini1, Vandana Sachdev1, and Andrew E Arai1

1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, 2Physiology Department, Northwestern University, Chicago, IL, United States, 3Computational Neuroscience, IBM / Thomas J Watson Center, Yorktown Heights, NY, 4Cardiology and Radiology, Hofstra Northwell School of Medicine, Manhasset, NY, United States

The purpose of this study was to investigate the magnitude of ex vivo static phantom corrections affecting Qp, Qs, and the Qp-to-Qs ratio measurements in diagnosing patients with intracardiac shunts. In the patients with Cath as the reference standard, phantom correction improved both the bias as well as the limits of agreement for Qp and the Qp:Qs ratio. For Qs, phantom correction improved the bias but did not significantly change the limits of agreement. While phantom correction appears to improve phase contrast MRI measurements, the main benefit is limited to patients with Qp:Qs close to the important diagnostic threshold selected.

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