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Abstract #2889

Repeatability of perfusion parameters in free-breathing dynamic contrast-enhanced MRI of malignant hepatic tumors

Bohyun Kim1, Kyung Won Kim2, Chang Kyung Lee3, Nieun Seo4, Seung Soo Lee2, and Jeong Kon Kim2

1Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea, Republic of, 2Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea, Republic of, 3Bioimaging Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, Republic of, 4Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of

In dynamic contrast-enhanced (DCE)-MRI, establishing a high level of repeatability is essential to ensure reliability of changes in perfusion parameters over longitudinal studies in an individual subject. To assess the repeatabilities of perfusion parameters and identify the effect of T1 map on them, we performed two sequential free-breathing DCE-MRI studies in patients with solid hepatic malignancies. Our results showed that Kep had the highest repeatability, and the repeatabilities of all perfusion parameters were boosted when fixed T1 value (800 ms) was used instead of values obtained from T1 mapping.

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