Abstract #2889

Repeatability of perfusion parameters in free-breathing dynamic contrast-enhanced MRI of malignant hepatic tumors

Bohyun Kim¹, Kyung Won Kim², Chang Kyung Lee³, Nieun Seo⁴, Seung Soo Lee², and Jeong Kon Kim²

¹Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea, Republic of, ²Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea, Republic of, ³Bioimaging Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, Republic of, ⁴Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of

In dynamic contrast-enhanced (DCE)-MRI, establishing a high level of repeatability is essential to ensure reliability of changes in perfusion parameters over longitudinal studies in an individual subject. To assess the repeatabilities of perfusion parameters and identify the effect of T1 map on them, we performed two sequential free-breathing DCE-MRI studies in patients with solid hepatic malignancies. Our results showed that K_ep had the highest repeatability, and the repeatabilities of all perfusion parameters were boosted when fixed T1 value (800 ms) was used instead of values obtained from T1 mapping.

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