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Abstract #2913

Quantitative ADC as an early imaging biomarker of response to chemoradiation in esophageal cancer

Benjamin Musall1, Jingfei Ma1, Brett Carter1, Penny Fang1, Amy Moreno1, Jong Bum Son1, Brian Hobbs1, Bryan Fellman1, and Steven Lin1

1The University of Texas MD Anderson Cancer Center, Houston, TX, United States

The goal of the study was to investigate if quantitative ADC can be used as an early imaging biomarker for predicting the treatment response to chemoradiation in esophageal cancer. Using pathological findings as the gold standard, our study demonstrated that the change in quantitative ADC from baseline (before treatment) to interim (two weeks after the initiation of treatment) was highly predictive of whether patients had residual tumors at the end of their treatment.

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