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Abstract #2980

Brain Metabolite Changes During Motor Task: A 3T functional MRS Study

Jay Hennessy1,2 and Jamie Near1,2

1Biomedical Engineering, McGill University, Montreal, QC, Canada, 2Brain Imaging Center, Douglas Mental Health Institute, Montreal, QC, Canada

Previous fMRS studies at 7T have shown changes in brain metabolite levels elicited by different stimuli. This 3T study employed a modified version of PRESS to effectively measure neurochemical changes generated by a finger tapping task during the MRS scan. The results show lactate in the motor cortex increased approximately 11%, while glutamate and aspartate trend toward a 2% increase and 3% decrease respectively. More subjects are required for further validation.

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