The most commonly used editing MRS method for measuring GABA is MEGA which works at TE=68 ms and any odd multiples thereof. Here we present a J-difference editing method which makes it possible to measure GABA signal at variable TEs independent of the effect of J-evolution by preserving the two side peaks of GABA in antiphase states at any echo time above 34ms. We also show an application of this editing technique to be measurement of T2 relaxation time of GABA in vivo.
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