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Abstract #3015

Qualitative Comparison between In Vivo J-Resolved Semi-LASER at 3 T and 9.4 T

Saipavitra Venkateshwaran Murali Manohar1, Ioannis Angelos Giapitzakis1, Tamas Borbath1, Matti Gaertner2, and Anke Henning1,3

1High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 2Department of Psychiatry, Charité - Universitätsmedizin Berlin, 3Institute of Physics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

J-resolved semi-LASER with maximum-echo sampling is optimized at 9.4T and compared with the same implementation at 3T in terms of SNR and spectral resolution. SODA scheme is appreciated for the sequence rather than the MC scheme. SNR at 9.4T (t1 steps: 85) was approximately 5.8 times greater than at 3T (t1 steps: 100) and strongly coupled peaks are well-resolved. However, the trade-off between SNR and spectral resolution is explained as lactate (1.32 ppm), a weakly-coupled metabolite, is better resolved at 3T. Higher band-width AFP pulses helped in almost vanishing the J-refocused peaks which made the J-resolved peaks clearly distinguishable. A few interesting downfield peaks and the doublet of NAA (7.82ppm) are observed.

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