Abstract #3042

Characterization and flip angle calibration of 13C surface coils for hyperpolarization studies

Rie B Hansen¹, Henrik Gutte², Majbrit ME Larsen³, Annemarie T Kristensen³, Andreas Kjær², Jan H Ardenkjær-Larsen¹, and Adam E Hansen²

¹Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark, ²Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ³Department of Veterinary Clinical and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

The aim of the present work is to address the challenge of optimal flip angle calibration of ¹³C surface coils in hyperpolarization studies. To this end, we characterize the spatial profile of the flip angle and demonstrate that it allows for a simple calibration improving the signal-to-noise ratio for hyperpolarized ¹³C magnetic resonance spectroscopic imaging.

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