The modified Look-Locker inversion-recovery (MOLLI) sequence is a widely used myocardial T1 mapping technique for tissue characterization. It is known that the MOLLI sequence underestimates myocardial T1 values (>10%) due to magnetization transfer (MT) effects and short myocardial tissue T2 values. In this work, we demonstrate that in vivo reduction of the inversion factor is predominantly responsible for the MT effect that reduces MOLLI T1 values. Thus, using an alternative T1 estimation algorithm with a measured inversion factor for the MOLLI sequence can reduce the MT effect on T1 estimation error.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords