Many non-mammalian vertebrates hold enormous potential as “model animals” for various fields of basic physiological and biomedical research. Hyperpolarized magnetic resonance imaging (MRI) can provide quantitative in vivo information about metabolic processes including major pathways of the citric acid cycle and glycolysis via spectral differences of pyruvate intermediates. The combination of [1-13C]-MRI and model animals exhibiting “selected physiological traits” may be a strong tool for gaining novel insights into relevant metabolic mechanisms. In this pilot study we test, for the first time, the application of [1-13C]-MRI in an ectothermic reptile.
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