Abstract #3115

Cardiac CEST MRI with Dual-Echo Readout for B0 Correction: A Preliminary Reproducibility Study for Assessment of Metabolic Activity in the Heart

Zhengwei Zhou^1,2, Xiaoming Bi³, and Debiao Li^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, ³MR R&D, Siemens Healthcare, Los Angeles, CA, United States

Previous studies have shown that cardiac CEST technique can detect myocardial metabolic abnormalities in chronic myocardial infarction. However, this navigator-gated technique is still sensitive to B₀ field variations caused by respiratory motion within the acceptance window.

In this work, we developed a cardiac CEST dual-echo technique which not only acquires CEST-weighted image, but also enables acquisition of B₀ map for each saturation frequency offset. The reproducibility of this technique was also assessed.

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