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Abstract #3122

Quantitative Multi-Contrast Atherosclerosis Characterization (qMATCH): Comprehensive Quantitative Evaluation of Atherosclerosis in a Single-Scan

Yibin Xie1, Anthony Christodoulou1, Nan Wang1,2, and Debiao Li1

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

Although MRI is an attractive imaging modality for the evaluation of carotid atherosclerosis thanks to its versatility and noninvasiveness, its current clinical usage is still limited. Major drawbacks of conventional protocols include long scan time and observer variability due to the qualitative nature of the images. In this work we proposed a fast, 3D, quantitative, multi-contrast MRI technique, qMATCH, for a comprehensive evaluation of carotid atherosclerosis in less than 8 minutes. Preliminary results from phantom and in vivo studies demonstrated excellent image quality and reliable quantification of tissue relaxation times.

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