Abstract #3123

Aortic Vessel Wall Imaging Using 3D Phase Sensitive Inversion Recovery in Children and Young Adults

Animesh Tandon^1,2, Tarique Hussain^1,2, Andrew Tran³, René M Botnar⁴, Gerald F Greil^1,2, and Markus Henningsson⁴

¹Pediatrics, Radiology, BME, University of Texas Southwestern Medical Center, Dallas, TX, United States, ²Pediatric Cardiology, Children's Medical Center Dallas, Dallas, TX, United States, ³Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, United States, ⁴Biomedical Engineering, King’s College, London, London, United Kingdom

Currently, T2-weighted TSE black blood zoom imaging (T2Z) is used to visualize atherosclerosis, but volumetric, high isotropic resolution datasets would be preferable. We compared aortic luminal sharpness (ALS) of a novel 3D bSSFP phase-sensitive inversion recovery black blood sequence (3DPSIR) to T2Z in 10 children and young adults with familial hypercholesterolemia at 5 aortic locations. 3DPSIR sequence duration was 7.0 minutes compared to 11.4 minutes for T2Z with no significant difference in ALS overall. 3DPSIR high resolution volumetric datasets will enable rapid, detailed 3D vessel wall imaging in children and young adults, allowing improved exploration of vascular health.

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