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Abstract #3158

Healthy aging of the left ventricle in relationship to cardiovascular risk factors:  The Multi-Ethnic Study of Atherosclerosis (MESA)

Chia-Ying Liu1, Shenghan Lai2, Nadine Kawel-Boehm3, Harjit Chahal4, Bharath Ambale-Venkatesh4, Joao Lima4, and David Bluemke5

1radiology and imaging sciences, national Institute of Health, bethesda, MD, United States, 2Johns Hopkins School of Medicine, 33Kantonsspital Graubuenden, Clinic of Radiology, 4Johns Hopkins Hospital, 5Radiology and Imaging Sciences, National Institutes of Health

We used cardiovascular magnetic resonance imaging to measure the LV and aortic structure and function in the Multi-Ethnic Study of Atherosclerosis (MESA). The cohort was divided into groups with or without traditional risk factors. In multivariable analyses adjusting for age, sex and race, individuals with risk factors had significantly larger LV mass index (by 17%) and lower LV contractibility (circumference strain, lower by 14%). LV structure and function are also better preserved in senescent hearts in the absence of traditional cardiovascular risk factors.

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