Abstract #3159

MRI Feature Tracking Strain Provides Incremental Prognostic Information Over Serum Biomarkers in AL Amyloidosis

Jeffery E Illman¹, James F Glockner¹, Ian C Chang², Arvin E Arani¹, Shivaram Poigai Arunachalam¹, Kiaran P McGee¹, Martha E Grogan², Angela E Dispenzieri³, and Philip A Araoz¹

¹Radiology, Mayo Clinic, Rochester, MN, United States, ²Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States, ³Department of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN, United States

The association of MRI feature tracking (FT) strain with all-cause mortality was retrospectively performed on 76 patients with new diagnosis of AL amyloid. Mean follow-up was 4 years. MRI FT radial, circumferential, and longitudinal strain were each associated with all-cause mortality in univariate analysis. In separate multivariate models with serum biomarker stage, radial, circumferential, and longitudinal strain each remained prognostic. This study shows the incremental prognostic value of MRI FT strain in AL amyloidosis.

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