The degree of pulmonary regurgitation has been a determinant for re-intervention for patients with repaired TOF. However, in practice, the accurate assessment of regurgitation may be interfered by the simultaneous existence of forward flow and backward flow in any single cardiac phase, which may mislead clinical decision making. In this study, we investigated the impact of heterogeneity in blood flow profiles on guiding management and the classification of regurgitation. Preliminary results suggest that pixel-wise reexamination may be required for reclassification, especially for patients with marginal moderate regurgitant fraction value.
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