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Abstract #3197

Quantitative Estimation of Liver Function using Gadoxetic Acid-Enhanced MR Imaging: in Vitro and in Vivo Comparison between R1 and R2* Relaxometry

Keitaro Sofue1,2, Masakatsu Tsurusaki3, Takamichi Murakami3, Katsusuke Kyotani4, Yu Ueda5, Tomoyuki Okuaki6, Satoru Takahashi1, Mustafa R. Bashir7,8, and Kazuro Sugimura1

1Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Center for Endovascular Therapy, Kobe University Hospital, Kobe, Japan, 3Radiology, Kinki University Faculty of Medicine, 4Division of Radiology, Kobe University Hospital, Kobe, Japan, 5Philips Electronics Japan, 6Philips Healthcare, 7Radiology, Duke University Medical Center, Durham, NC, United States, 8Center for Advanced Magnetic Resonance Development, Duke University Medical Center

R2* relaxometry that is simultaneously obtained on proton density fat fraction map in gadxetic acid-enhanced MRI can quantitatively estimate liver function. PDFF sequence can potentially quantify steatosis, iron overload, and liver function simultaneously.

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