Abstract #3199

Water-fat separated T1 mapping in the liver and correlation to hepatic fat fraction

Claudia Fellner¹, Philipp Wiggermann¹, Dominik Nickel², Niklas Verloh¹, Stephan Kannengießer², Christian Stroszczynski¹, and Michael Haimerl¹

¹Institute of Radiology, University Hospital Regensburg, Regensburg, Germany, ²MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany

Fat signal fraction (FF) and R2* mapping as well as MRS of the liver were performed in 201 patients. Results for FF from imaging and MRS were compared to a newly defined parameter T1_FF. T1_FF was calculated from a variable flip angle 3D GRE technique with 2 echo times. Based on the Dixon method, T1 maps from in-phase and from water signal were calculated and T1_FF was deduced. T1_FF correlated well with FF and might be used as a novel estimation of fat fraction. Relevant discrepancies were seen in cases with high R2*.

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